Journal
NANOSCALE
Volume 12, Issue 13, Pages 6959-6963Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0nr01138j
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Funding
- Tumor Heterogeneity and Ecosystem program of Plan Cancer 2014-2019 [C16080CS]
- Plan Cancer 2014-2019 [C18038CS]
- Canceropole Lyon Auvergne Rhone-Alpes
- Fondation ARC [R17157CC]
- Region Rhone Alpes (Pack Ambition Recherche)
- Fondation pour la Recherche Medicale
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Ultra-small gold nanoclusters (AuNCs) are increasingly investigated for cancer imaging and radiotherapy enhancement. While fine-tuning the AuNC surface chemistry can optimize their pharmacokinetics, its effects on radiotherapy enhancement remain largely unexplored. This study demonstrates that optimizing the surface chemistry of AuNCs for increased tumor uptake can significantly affect its potential to augment radiotherapy outcomes.
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