4.6 Article

The Future of Origin of Life Research: Bridging Decades-Old Divisions

Journal

LIFE-BASEL
Volume 10, Issue 3, Pages -

Publisher

MDPI
DOI: 10.3390/life10030020

Keywords

origins of life; prebiotic chemistry; early life; LUCA; abiogenesis; top-down; bottom-up; emergence

Funding

  1. Deutsche Forschungsgemeinschaft [MA-1426/21-1]
  2. European Research Council [666053]
  3. Volkswagen Foundation [93046]
  4. Origins Center through NWA StartImpuls
  5. European Structural and Investment Funds Operational Programme Research, Development and Education [C.Z. 02.2.69/0.0/0.0/16_027/0008351]
  6. Research Encouragement Fund UKM [GGP-2019-029]
  7. European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme [803768]
  8. Wiener Wissenschafts-, Forschungs-und Technologiefonds [VRG15-007]
  9. National Research, Development and Innovation Office (NKFIH) [GINOP 2.3.2-15-2016-00057]
  10. CRC 235 Emergence of Life
  11. European Research Council (ERC) [724908-Habitat OASIS]
  12. NERC GW4 PhD studentship
  13. European Research Council (ERC) [803768] Funding Source: European Research Council (ERC)

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Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress. In the 1st Interdisciplinary Origin of Life Meeting, early-career researchers gathered to explore the commonalities between theories and approaches, critical divergence points, and expectations for the future. We find that even though classical approaches and theories-e.g., bottom-up and top-down, RNA world vs. metabolism-first-have been prevalent in origin of life research, they are ceasing to be mutually exclusive and they can and should feed integrating approaches. Here we focus on pressing questions and recent developments that bridge the classical disciplines and approaches, and highlight expectations for future endeavours in origin of life research.

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