Journal
POLYMER CHEMISTRY
Volume 11, Issue 15, Pages 2630-2634Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0py00117a
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Funding
- Science & Engineering Research Board, Department of Science and Technology, New Delhi, India [CRG/2018/001795]
- FIST, DST, New Delhi
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Glycine, a biomolecule, has been functionalized through a simple condensation reaction with one of two functional groups (-COOH and -NH2) to prepare two vinylic monomers. On the other hand, glycogen has been methacrylated (Gly-Meth) to incorporate a polymerizable vinylic group. Finally, two different hydrogels, with reversible swelling characteristics, have successfully been synthesised through polymerization of each of these two monomers with Gly-Meth. The developed hydrogels with different connectivity demonstrate a superb pH responsive sustained release behaviour of model drugs (ciprofloxacin and naproxen).
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