Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 26, Pages 3773-3776Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc00067a
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Funding
- National Natural Science Foundation of China [U1732130, 81672736]
- Key Research Program of Frontier Sciences of the Chinese Academy of Sciences [QYZDJ-SSW-SLH019]
- Shanghai Municipal Science and Technology Major Project [2017SHZDZX01]
- National Key R&D Program of China [2018YFC0910500]
- Scientific Research Foundation of Binzhou Medical University [BY2017KYQD02]
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The influence of cell number on spectral variability among two different cell types and two states was quantitatively analyzed and evaluated by calculating the similarity distance of the single-cell spectral data obtained from synchrotron infrared microspectroscopy. We found that at least 15 cells are required to achieve robust results with 95% confidence.
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