Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 58, Issue 1, Pages 17-22Publisher
IOS PRESS
DOI: 10.3233/JAD-161190
Keywords
Adults; cognition; executive function; exercise; resistance training; saccades
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Funding
- Canadian Institutes of Health Research [MOP 130474]
- St. Joseph's Health Care Foundation [0481415]
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Adults (>= 55 years) with self-reported cognitive complaints (sCC) were randomized to: multiple-modality exercise (M2), or multiple-modality plus mind-motor exercise (M4), for 24-weeks. Participants (n = 58) were assessed on antisaccade reaction time (RT) to examine executive-related oculomotor control and self-reported physical activity (PA) at pre-intervention (V0), post-intervention (V1), and 52-weeks follow-up (V2). We previously reported significant improvements in antisaccade RT of 23 ms at V1, in both groups. We now report maintenance of antisaccade RT improvement from V1 to V2, t(57) = 0.8, p = 0.45, and improved PA from V1 to V2, t(56) = -2.4, p = 0.02. Improvements in executive-related oculomotor control attained at V1 were maintained at V2.
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