4.7 Article

A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 18, Pages 2695-2698

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc00027b

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Funding

  1. State Key Laboratory of Environmental and Biological Analysis
  2. HKBU

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A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.

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