Journal
INVESTIGATIVE AND CLINICAL UROLOGY
Volume 61, Issue 3, Pages 260-268Publisher
KOREAN UROLOGICAL ASSOC
DOI: 10.4111/icu.2020.61.3.260
Keywords
Carcinoma; Carcinoma; renal cell; Mortality; Prognosis
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Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [2017R1A2B4005876]
- National Research Foundation of Korea [2017R1A2B4005876] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Purpose: To develop the clinical calculator for mortality of patients with metastatic renal cell carcinoma (mRCC) using Korean Renal Cancer Study Group (KRoCS) database. Materials and Methods: Data from 1,115 patients with mRCC treated in 4 hospitals joining KRoCS between 1993 and 2016 were pooled. Five-year survival rates were calculated using Kaplan-Meier curve. A clinical calculator for 5-year mortality was developed using multivariable logistic regression analysis and validated externally using dataset including 916 patients from 4 other hospitals. Results: Overall survival rates and cancer specific survival rate at 5 years were 28.5% and 29.4%, respectively. Among baseline factors, increased neutrophil-lymphocyte ratio (>= 4), synchronous metastasis, low albumin (<3.0 g/dL), and low hemoglobin (
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