Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 34, Pages 4672-4675Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc07931a
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Funding
- EPSRC [EP/P511122/1]
- Wellcome Trust [202056/Z/16/Z]
- European Social Fund & Tenovus Cancer Care (Knowledge Economy Skills Scholarship)
- Welsh Government (Life Sciences Research Network Wales Scholarship)
- Wellcome Trust [202056/Z/16/Z] Funding Source: Wellcome Trust
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Organelle-specific delivery systems are of significant clinical interest. We demonstrate the use of common cyanine dyes Cy3 and Cy5 as vectors for targeting and delivering cargoes to mitochondria in cancer cells. Specifically, conjugation to the dyes can increase cytotoxicity by up to 1000-fold.
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