Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 34, Pages 4720-4723Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc01810d
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Funding
- JSPS KAKENHI [JP19K05451, JP18J11113, JP18H02104, JP18H04386]
- Naito Foundation
- Japan Agency for Medical Research and Development (AMED) [JP19am0101098]
- Cooperative Research Project of Research Center for Biomedical Engineering
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An efficient method to assemble three cycloalkyne-modules onto a platform compound bearing a thiophene S,S-dioxide moiety and two azido groups has been developed. The sequential reactions without catalysis or additives enabled the facile preparation of trifunctional molecules by a simple procedure. One-pot assembly was also achieved using the platform and three cycloalkynes.
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