4.6 Review

Micromotor-derived composites for biomedicine delivery and other related purposes

Journal

BIO-DESIGN AND MANUFACTURING
Volume 3, Issue 2, Pages 133-147

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s42242-020-00072-w

Keywords

Micromotor; Propulsion; Targeted delivery; Retention; Penetration

Funding

  1. National Natural Science Foundation of China [51472115]
  2. Jiangsu Provincial Graduate Research Innovation and Practice Project [KYCX17_0672, KYCX19_0645]
  3. Research Program of Natural Science in Huaian [HAB201717]
  4. Jiangsu Overseas Research & Training Program for University Young Faculty and Presidents

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Biocompatible designed micromotor has attracted more and more concerns in the field of biomedicine due to their self-propulsion and delivery abilities. Such micromotors, mostly consisting of alkali earth metals, hydrogels, or other motile biomaterials, can effectively transform chemical energy into mechanical or kinetic energy to achieve the expected delivery of cargos to the sites of action. Except for conveying power, the modifiable surface and inner cavity of micromotors guarantee that their potential as versatile delivery systems for therapeutic agents. Here, this review generalizes the propelling mechanisms, composites, and shapes of micromotors. Besides, the application of micromotor-derived composites for biomedicine delivery and other versatile purposes are also discussed.

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