Journal
NEW JOURNAL OF CHEMISTRY
Volume 44, Issue 17, Pages 7091-7095Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0nj01504k
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Funding
- National Natural Science Foundation of China [21775096, 21907062]
- One hundred people plan of Shanxi Province
- Shanxi Province 1331 project'' key innovation team construction plan cultivation team [2018CT-1]
- 2018 Xiangyuan County Solid Waste Comprehensive Utilization Science and Technology Project [2018XYSDJS-05]
- Shanxi Province Foundation for Returness [2017-026]
- Shanxi Collaborative Innovation Center of High Value-added Utilization of Coal-related Wastes [2015-10-B3]
- Shanxi Province annual science and technology activities for overseas students selected funding projects (2019)
- Innovative Talents of Higher Education Institutions of Shanxi (2019)
- Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi [2019L0031, 201802010]
- Key R&D Program of Shanxi Province [201903D421069]
- Natural Science Foundation of Shanxi Province of China [201901D111015]
- Program for the Innovative Talents of Higher Education Institutions of Shanxi (2019)
- China Institute for Radiation Production and Scientific Instrument Center of Shanxi University [201512]
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As an important small gas signal molecule, H2S has become an important research hotspot for both chemists and biologists. Therefore, we designed and synthesized a benzene-conjugated coumarin connected to 2,4-dinitrobenzene via an oxygen atom (P1) to detect H2S and explored its applications in biological imaging. After 40 minutes of long-time irradiation and different pH tests, we found that P1 has good photostability and chemical stability, indicating that P1 had the ability to detect H2S accurately. In addition, P1 has a fast response speed, low detection limit and low toxicity. Based on these characteristics, P1 was used to detect H2S in live cell imaging.
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