Natural product diversity from the endophytic fungi of the genusAspergillus

The endophytic fungusAspergillusis considered as an enormous source of chemical leads with promising biological activities. DifferentAspergillusspecies have proved their ability to produce plenty of secondary metabolites including butenolides, alkaloids, terpenoids, cytochalasins, phenalenones, rho-terphenyls, xanthones, sterols, diphenyl ether and anthraquinone derivatives with diverse biological activities, such as anti-cancer, antifungal, anti-bacterial, anti-viral, anti-inflammatory, antitrypanosomal and antileishmanial activities. From January 2015 until December 2019, three hundred and sixty-one secondary metabolites were reported from different endophyticAspergillusspecies. This review discusses the isolated secondary metabolites from different endophyticAspergillusspecies reported from January 2015 to December 2019 along with their reported biological activities and structural aspects whenever applicable.