Journal
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY
Volume 35, Issue 3, Pages 274-284Publisher
SPRINGER INDIA
DOI: 10.1007/s12291-020-00900-x
Keywords
Covid-19; Hydroxychloroquine; Cytokine storm; Severe acute respiratory syndrome coronavirus 2
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As the time for finding a definitive and safe cure as a vaccine for novel Corona Virus Disease 2019 (Covid-19) is still far, there is need to study in depth about the other potential drugs, which can save millions of lives due to Covid-19 pandemic. Right at the center of the debate is the use of drug Hydroxychloroquine as a prophylaxis as well as a treatment strategy against Covid-19 in conjunction with azithromycin. In this review, we will study the cellular and molecular aspects of hydroxychloroquine, which had driven its use in Covid-19 patients, as well as its chemistry and pharmacokinetics along with clinical trials going on worldwide using hydroxychloroquine against Covid-19.
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