4.5 Article

Oxidative Stress and Parkinson's Disease: New Hopes in Treatment with Herbal Antioxidants

Journal

CURRENT PHARMACEUTICAL DESIGN
Volume 22, Issue 2, Pages 238-246

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1381612822666151112151653

Keywords

Antioxidant; degenerative disorder; herbal medicines; medicinal plants; oxidative stress; Parkinson's isease

Funding

  1. Research and Technology Deputy of Shahrekord University of Medical Sciences

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Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.

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