4.7 Article

A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 40, Pages 5441-5444

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc01025a

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Funding

  1. National Natural Science Foundation of China [21174077]
  2. Beijing Natural Science Foundation Program and Scientific Research Key Program of Beijing Municipal Commission of Education [KZ201510025023]

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A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

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