Journal
CURRENT PHARMACEUTICAL ANALYSIS
Volume 12, Issue 1, Pages 4-17Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573412911666150505185343
Keywords
Oxidative stress; biomarker; malondialdehyde; serum analysis; bioanalysis; review
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Funding
- Tabriz University of Medical Sciences
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Malondialdehyde (MDA) is one of the most common biomarkers of oxidative stress and is used for the diagnosis of many diseases. This work aims to review the reaction used for the derivatization of MDA, the parameters affecting adduct formation, and a number of recently published analytical methods for quantification of MDA in biological samples. A brief discussion of the reliability of MDA as an oxidative stress biomarker is also provided.
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