Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume 67, Issue 12, Pages 739-744Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2017.1376200
Keywords
Antibacterial; biomedical; composite nanofibers; electrospinning
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Funding
- National Research Foundation of Korea [2014R1A4A1008140] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Salicylic acid (SA)/polyurethane (PU) composite nanofiber mats were fabricated by introducing SA in PU solution during the electrospinning process. Cell viability assays showed that the as-prepared composite nanofibers had a good biocompatibility. Further, the composite mats showed good antibacterial performance against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacteria. Easy fabrication, good mechanical properties, good biocompatibility as well as the antibacterial activity of PU nanofibers containing SA indicated their significant promise for a variety of potential medical applications such as tissue engineering, wound healing, and drug delivery system. [GRAPHICS] .
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