4.7 Article

Possible Bat Origin of Severe Acute Respiratory Syndrome Coronavirus 2

Journal

EMERGING INFECTIOUS DISEASES
Volume 26, Issue 7, Pages 1542-1547

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2607.200092

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Funding

  1. theme-based research scheme of the University Grant Committee [T11-707/15-R]
  2. Health and Medical Research Fund of the Food and Health Bureau of HKSAR
  3. Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Disease for the HKSAR Department of Health
  4. University Development Fund of the University of Hong Kong

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We showed that severe acute respiratory syndrome coronavirus 2 is probably a novel recombinant virus. Its genome is closest to that of severe acute respiratory syndrome-related coronaviruses from horseshoe bats, and its receptor-binding domain is closest to that of pangolin viruses. Its origin and direct ancestral viruses have not been identified.

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