Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 8, Issue 22, Pages 4841-4845Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0tb00097c
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Funding
- National Natural Science Foundation of China [81503259]
- Jiangsu Natural Science Foundation of China [BK20151002]
- Young Elite Scientists Sponsorship Program by CAST, the China [2017QNRC001]
- Jiangsu Postdoctoral Science Foundation [2016M591813, 1601238C]
- Six Talent Peaks Project of Jiangsu Province [SWYY-057]
- 333 Project
- QingLan Project
- Program for Outstanding Scientific and Technological Innovation Team of Jiangsu Higher Education Institutions
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We herein report a hybrid nanocomposite (AuNRs-CTN@THA) which is based on hyaluronic acid-coated gold nanorods with loading of a copper complex through strong bonds. AuNRs-CTN@THA exhibits durable photothermal conversion capacity for pH-dominant and pH/temperature dual sensitive drug release, accomplishing synergetic antitumor efficacy and deep tumor penetration.
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