Journal
ANALYST
Volume 145, Issue 12, Pages 4260-4264Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0an00795a
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Funding
- National Natural Science Foundation of China [21874023]
- Ministry of Education of the People's Republic of China [IRT15R11]
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Copper (Cu) is a vital metal element for humans and animals. Monitoring and evaluating the concentration level of Cu(2+)in a biological body is an effective way to prevent a variety of diseases. In this work, phenyl doped graphitic carbon nitride (PDCN) nanosheets with strong green fluorescence exhibited a sensitive and selective detection for Cu(2+)with a linear range from 0.1-2.0 mu mol L-1. Furthermore, fluorescent imaging was applied to semiquantitatively detect Cu(2+)in HeLa cells using PDCN nanosheets as the probe, which can avoid the interference of background autofluorescence. This work provided a low-cost and biologically friendly fluorescent probe to monitor the concentration level of Cu(2+)in living cells.
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