4.8 Article

Ru-catalyzed isomerization of ω-alkenylboronates towards stereoselective synthesis of vinylboronates with subsequentin situfunctionalization

Journal

CHEMICAL SCIENCE
Volume 11, Issue 23, Pages 5944-5949

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0sc02542a

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Funding

  1. European Union [786976]
  2. European Research Council (ERC) [786976] Funding Source: European Research Council (ERC)

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The stereoselective preparation of synthetically versatile vinylboronates from omega-alkenylboronates is achieved through a ruthenium-catalyzed isomerization reaction. A variety of di- and trisubstituted vinylboronates were conveniently produced and could be used as a new starting point for subsequentin situremote functionalization through either a sequential Ru/Pd or Ru/Cu double catalytic system.

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