Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 7, Issue 13, Pages 1690-1695Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0qo00367k
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Funding
- National Science Foundation of China [NSFC-21672035]
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We have developed a highly regioselective halothiolation of alkynes under simple and mild conditions. Our halothiolation reagents are readily available alkali metal halides andN-thiosuccinimides. Our transition metal-free system offers good chemical yields for a wide range of alkyne substrates with satisfactory regioselectivity and good functional group tolerance.
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