Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 32, Issue -, Pages 80-85Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2015.01.002
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Funding
- NIH [GM083997, HL110335, HL118532, HL120142]
- NSF [CMMI-1435853]
- David & Lucile Packard Foundation
- Alfred P. Sloan Foundation
- Camille & Henry Dreyfus Foundation
- Burroughs Wellcome Fund
- NSF Graduate Research Fellowship Program
- Directorate For Engineering
- Div Of Civil, Mechanical, & Manufact Inn [1435853] Funding Source: National Science Foundation
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Forces arising from contractile actomyosin filaments help shape tissue form during morphogenesis. Developmental events that result from actomyosin contractility include tissue elongation, bending, budding, and collective migration. Here, we highlight recent insights into these morphogenetic processes from the perspective of actomyosin contractility as a key regulator. Emphasis is placed on a range of results obtained through live imaging, culture, and computational methods. Combining these approaches in the future has the potential to generate a robust, quantitative understanding of tissue morphodynamics.
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