Journal
INTERNATIONAL JOURNAL OF HEMATOLOGY
Volume 105, Issue 6, Pages 711-719Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s12185-017-2243-z
Keywords
Chronic myelomonocytic leukemia; Myelodysplastic; Myeloproliferative
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Chronic Myelomonocytic Leukemia is a chronic myeloid neoplasm occurring mostly in the elderly with overlapping features of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN) characterized by chronic monocytosis. Recent progresses in the molecular and cellular pathogenesis of CMML have stirred a renewed interest in this clinically heterogeneous disorder. Here, we review the recent progresses in the biology of CMML and how it affects its current and future clinical management.
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