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Biocatalysts for biomass deconstruction from environmental genomics

Journal

CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 29, Issue -, Pages 18-25

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2015.06.032

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Funding

  1. Natural Sciences and Engineering Research Council (NSERC) of Canada
  2. Genome British Columbia
  3. Genome Alberta
  4. Genome Canada
  5. Canada Foundation for Innovation (CFI)
  6. Tula Foundation funded Centre for Microbial Diversity and Evolution
  7. Canadian Institute for Advanced Research (CIFAR)
  8. NSERC CREATE Genome Sciences and Technology (GSAT) training program at the University of British Columbia

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Plant biomass offers a sustainable alternative to the energy and materials produced from fossil fuels. The industrial scale production or biorefining of fermentable sugars and aromatics from plant biomass is currently limited by the lack of cost effective and efficient biocatalysts. One potential solution to this problem is the discovery of biomass deconstructing biocatalysts from uncultivated microbial communities. Here we review recent progress in recovering such biological devices from environmental genomes and consider how this information can be used to build better biorefining ecosystems.

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