Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 24, Issue -, Pages 121-130Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2014.11.006
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Funding
- National Science Foundation [CBET-1351302]
- Research Corporation (Cottrell Scholars Program)
- BEST IGERT program - National Science Foundation [DGE-1144901]
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [1351302] Funding Source: National Science Foundation
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Cellular communication drives diverse aspects of organismal biology ranging from immune function to memory formation. The mechanisms by which cells transact information in vivo, though, are not completely understood. This is due, in part, to a lack of tools for observing collections of cells in their native habitats. New optical probes are being crafted to image networks of cell-cell interactions (i.e., 'interactomes) in tissues and live organisms. Examples of these - probes and their use in visualizing cell contacts and macroscopic cell networks - are highlighted.
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