4.5 Article

Effects of endocytosis on receptor-mediated signaling

Journal

CURRENT OPINION IN CELL BIOLOGY
Volume 35, Issue -, Pages 137-143

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2015.05.005

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Funding

  1. U.S. National Institutes of Health
  2. NIH/NHLBI [K99/R00]
  3. American Heart Association
  4. NIH/NIDA

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Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The present review discusses how membrane trafficking in the endocytic pathway impacts receptor-mediated signaling. Examples of recent progress are highlighted, focusing on the endocytosis-signaling nexus in mammals.

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