Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 32, Issue -, Pages 1-6Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2014.09.007
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Funding
- Institut National de la Sante et de la Recherche Medicale
- Universite Pierre et Marie Curie Paris 06
- Centre National de la Recherche Scientifique
- COST action [BM1002]
- Cure-CMD Mid Range Grant
- Cure-CMD Short Range Grant
- Association Francaise contre les Myopathies
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The nuclear lamina is a mesh-like network of intermediate filaments localized mainly at the inner surface of the inner nuclear membrane and is composed of proteins called lamins. Many inherited diseases are linked with mutations in nuclear lamins and integral proteins of the inner nuclear membrane. In this article, we summarize basic aspects of the nuclear envelope architecture and provide some remarkable findings of the involvement of lamins in striated muscle disorders.
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