Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 32, Issue -, Pages 216-222Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2015.01.004
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Funding
- Biotechnology and Biological Sciences Research Council [BB/L011484/1]
- National Science Foundation [NSF-1331098]
- Biotechnology and Biological Sciences Research Council [BB/L011484/1] Funding Source: researchfish
- Direct For Biological Sciences
- Division Of Integrative Organismal Systems [1331098] Funding Source: National Science Foundation
- BBSRC [BB/L011484/1] Funding Source: UKRI
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Engineering cereal crops that are self-supported by nitrogen fixation has been a dream since the 1970s when nitrogenase was transferred from Klebsiella pneumoniae to Escherichia coli. A renewed interest in this area has generated several new approaches with the common aim of transferring nitrogen fixation to cereal crops. Advances in synthetic biology have afforded the tools to rationally engineer microorganisms with traits of interest. Nitrogenase biosynthesis has been a recent target for the application of new synthetic engineering tools. Early successes in this area suggest that the transfer of nitrogenase and other supporting traits to microorganisms that already closely associate with cereal crops is a logical approach to deliver nitrogen to cereal crops.
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