Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 31, Issue -, Pages 1-9Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2014.07.008
Keywords
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Funding
- US Department of Energy, Office of Science, Office of Biological and Environmental Research [DE-AC02-05CH11231]
- Direct For Biological Sciences [1341894] Funding Source: National Science Foundation
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1341414] Funding Source: National Science Foundation
- Div Of Molecular and Cellular Bioscience [1341894] Funding Source: National Science Foundation
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Mass spectrometry imaging (MSI) has found a diversity of applications ranging from localizing metabolites and proteins in tissues to investigating microbial interactions, and as a result is perhaps the fastest growing subfield of mass spectrometry. Advances in surface mass spectrometry technologies are equally applicable to the analysis of arrayed samples. One promising field in which this capacity has been leveraged is the high-throughput analysis of enzyme activity, an important step in the development of a wide range of biotechnologies. This review article describes several emerging approaches that seek to improve the quality and scope of this application of MSI.
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