Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 34, Issue -, Pages 73-81Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.copbio.2014.11.022
Keywords
-
Funding
- Belgian American Educational Foundation (BAEF)
- FWO
- Federal Government Belgium grant [IUAP P7/03]
- Flemish Government
- Belgian Science Fund (FWO) [G.0817.11, 0578.12, 0834.13]
- Foundation of Leducq Transatlantic Artemic Network
- European Research Council (ERC)
- AXA Research Fund
Ask authors/readers for more resources
For eukaryotic cells to function properly, they divide their intracellular space in subcellular compartments, each harboring specific metabolic activities. In recent years, it has become increasingly clear that compartmentalization of metabolic pathways is a prerequisite for certain cellular functions. This has for instance been documented for cellular migration, which relies on subcellular localization of glycolysis or mitochondrial respiration in a cell type-dependent manner. Although exciting, this field is still in its infancy, partly due to the limited availability of methods to study the directionality of metabolic pathways and to visualize metabolic processes in distinct cellular compartments. Nonetheless, advances in this field may offer opportunities for innovative strategies to target deregulated compartmentalized metabolism in disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available