Journal
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Volume 12, Issue 12, Pages 11224-11234Publisher
ESG
DOI: 10.20964/2017.12.36
Keywords
Polycystic ovarian syndrome; Electrochemical impedance immunosensor; Testosterone; Saliva; Biosynthesis
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Funding
- Harbin medical university scientific research innovation fund of Harbin medical university scientific research innovation fund [20161czx58]
- Health and family planning commission research project in heilongjiang province [2017-021]
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Polycystic ovarian syndrome (PCOS) is a disease that occurs extensively among females during their reproductive period and that can be diagnosed using the testosterone level in the body. In the present report, a biosynthesized gold nanoparticle (AuNP)-based electrochemical impedance immunosensor was fabricated for the first time and used for the detection of testosterone with a wide detection range of 10 ng/mL - 0.5 mu g/mL. In addition, our proposed immunosensor showed excellent performance in the detection of testosterone in saliva specimens.
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