Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 32, Issue -, Pages 207-215Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2014.12.025
Keywords
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Funding
- NIH [R01 GM093008]
- NSF Career Award [MCB-0642843]
- NSF [IOS-1257576]
- California Department Food & Agriculture Award [CDFA-SCB12057]
- Citrus Research Board [5100-131]
- AES-CE Award [PPA-7517H]
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [1257576] Funding Source: National Science Foundation
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Humans, animals, and plants are constantly under attack from pathogens and pests, resulting in severe consequences on global human health and crop production. Small RNA (sRNA)-mediated RNA interference (RNAi) is a conserved regulatory mechanism that is involved in almost all eukaryotic cellular processes, including host immunity and pathogen virulence. Recent evidence supports the significant contribution of sRNAs and RNAi to the communication between hosts and some eukaryotic pathogens, pests, parasites, or symbiotic microorganisms. Mobile silencing signals most likely sRNAs are capable of translocating from the host to its interacting organism, and vice versa. In this review, we will provide an overview of sRNA communications between different kingdoms, with a primary focus on the advances in plant pathogen interaction systems.
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