Journal
BIOMATERIALS SCIENCE
Volume 8, Issue 15, Pages 4052-4066Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0bm00526f
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Funding
- National Natural Science Foundation of China [21875210]
- Fundamental Research Funds for the Central Universities [2017XZZX001-03B, 2019XZZX005-1-03]
- Higher Education Discipline Innovation Project (111 Project) [B16042]
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Pathogenic microbial biofilms that readily form on implantable medical devices or human tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive strategies towards biofilms, leaving a thought-provoking question: how to tackle the problem of established biofilms? In this review, we briefly summarize the functionalized biomaterials to combat biofilms and highlight current approaches to eradicate pre-existing biofilms. We believe that all of these strategies, alone or in combination, could represent a blueprint for fighting biofilm-associated infections in the postantibiotic era.
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