Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 104, Issue -, Pages 1882-1889Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2017.02.041
Keywords
Chitin nanofiber; Gelatin; Composite
Funding
- Japan Society for the Promotion of Science [26708026]
- Grants-in-Aid for Scientific Research [26708026] Funding Source: KAKEN
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The development of chitin-based materials with favorable mechanical properties and biocompatibility is an important research goal owing to the wide-ranging practical applications. In this study, a composite film was prepared using chitin nanofibers and gelatin. The CNF/gelatin composite film was highly viscous and had a fine nanofiber structure. The transmittances indicated high transparency, regardless of nanofiber content. The water content of the CNF/gelatin composite film increased linearly as the gelatin content increased. Although the CNF/gelatin composite film did not induce severe inflammation, it strongly induced fibroblast proliferation, indicating high biocompatibility. Based on these results, the films are suitable for biological applications, e.g., tissue engineering, medicines, and cosmetics. (C) 2017 Elsevier B.V. All rights reserved.
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