Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 97, Issue -, Pages 778-789Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2016.11.014
Keywords
Intrinsically disordered proteins; Membrane proteins; Inclusion bodies; Crosslinked enzyme aggregates (CLEAs); Three phase partitioning of proteins; Food proteins; Caseins; Enzymes in detergents
Funding
- Department of Science and Technology (DST) [Govt. of India] [SR/SO/BB-68/2010]
- Department of Biotechnology (DBT) [Govt. of India] [BT/PR14103/BRB/10/808/2010]
- Department of Biotechnology (DBT) [Govt. of India]
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Protein aggregation is implicated in diverse biochemical phenomena which include formation of inclusion bodies and amyloids. In recent years, inclusion bodies of many enzymes have been found to be catalytically active. Enzyme precipitates and their crystalline aggregates have found extensive applications in Biocatalysis in low water media. Protein aggregates also play a useful role in processed food. Enzymes are incorporated in detergents in the form of granulates. This review also looks at the various techniques which are used for characterizing protein aggregates. (C) 2016 Elsevier B.V. All rights reserved.
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