Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 8, Issue 31, Pages 6517-6529Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0tb00713g
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Funding
- Anesthesia Research Distinguished Trailblazer Award (2019) from Boston Children's Hospital
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Peptides are one of the most important functional motifs for constructing smart drug delivery systems (DDSs). Functional peptides can be conjugated with drugs or carriersviacovalent bonds, or assembled into DDSsviasupramolecular forces, which enables the DDSs to acquire desired functions such as targeting and/or environmental responsiveness. In this mini review, we first introduce the different types of functional peptides that are commonly used for constructing DDSs, and we highlight representative strategies for designing smart DDSs by using functional peptides in the past few years. We also state the challenges of peptide-based DDSs and come up with prospects.
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