Cyanobacterial polyhydroxybutyrate for sustainable bioplastic production: Critical review and perspectives

PHB is a promising bioplastic material that naturally accumulates in many strains of cyanobacteria. This comprehensive review covers recent advances in several topics including PHB metabolism, material properties, relevant extraction methods and protocols, industrial cultivation strategy, current economic assessment and much more. Ultimately, the profitability of cyanobacterial PHB production is controlled by low PHB productivity as well as expensive cultivation and harvesting equipment. Several research areas for improving viability of cyanobacterial PHB production have also been summarised and perspectives on future efforts suggested including; screening, genetic modification, wastewater cultivation and using chemical modulators among others.