Synthesis of polymeric bismuth chlorido hydroxamato complexes; X-ray crystal structure and antibacterial activity of a novel Bi(III) salicylhydroxamato complex

Reaction of salicylhydroxamic acid (Sha) and 2-aminophenyl hydroxamic acid (2-NH2-pha) with BiCl3 affords the corresponding novel polymeric bismuth chlorido hydroxamato complexes; [BiCl2(mu-Sha-(1H))](infinity) and [BiCl3(2-NH3-Pha-(1H))](infinity) respectively. The X-ray crystal structure of the THF-solvated polymeric bismuth chlorido salicylhydroxamato complex, [BiCl2(mu-Sha-(1H))(THF)](infinity) was solved, confirming the polymeric structure of this class of compounds and the (O, mu-O')-bidentate bridging coordination mode of the hydroxamato ligand. The antibacterial activity of the THF-free polymeric bismuth chlorido salicylhydroxamato complex, [BiCl2(mu-Sha-(1H))](infinity), was investigated against a broad panel of bacteria, further highlighting the antibacterial properties of Bi-based compounds against Gram-positive and Gram-negative pathogenic and environmental strains of bacteria. (C) 2016 Elsevier B.V. All rights reserved.