Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 25, Issue -, Pages 1259-1296Publisher
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/4855
Keywords
Phytoconstituents; Osteoporosis; Bone health; Bone loss; Osteo-protective and Review
Categories
Funding
- DST-SERB, Govt. of India [EMR/2016/007158]
- All India Institute of Medical Sciences (AIIMS), New Delhi-India
- ICMR
- UGC-NFST
- CSIR
- DST
- DBT
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Osteoporosis is a progressive and chronic bone disorder characterized by low bone mass and microarchitectural deterioration of skeletal tissues. Osteoporosis leads to alteration in bone mineral content resulting in decreased bone strength with elevated fracture risks frequently associated with greater morbidity. The latest research in the area of photomedicine had sparked interest in harnessing the active components from plants in both disease control and management across the globe. We in the present review have taken a comprehensive approach to identify forty known plants and their phytoconstituents, which encompasses (i) the genetic diversity of various plants, (ii) their active components and (iii) their osteoprotective role in osteoporosis. Thus, the present review is an attempt for the first time to collectively document the therapeutic properties of valuable medicinal plants in preventing and treating bone loss in osteoporosis.
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