Journal
CURRENT DRUG TARGETS
Volume 16, Issue 6, Pages 571-581Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389450116666150707100328
Keywords
Drug delivery; image-guided therapy; optoacoustic; photoacoustic; photothermal; theranostics
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Funding
- National Institutes of Health [R01EB017270]
- Korean Ministry of Science, ICT and Future Planning (IT Consilience Creative Program) [NIPA-2013-H0203-13-1001, NRF-2011-0030075]
- NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R01EB017270] Funding Source: NIH RePORTER
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Photoacoustic imaging (PAI) is rapidly becoming established as a viable imaging modality for small animal research, with promise of near-future human clinical translation. In this review, we discuss emerging prospects for photoacoustic-guided drug delivery. PAI presents opportunities for applications related to drug delivery, mainly with respect to either monitoring drug effects or monitoring drugs themselves. PAI is well-suited for imaging disease pathology and treatment response. Alternatively, PAI can be used to directly monitor the accumulation of various light-absorbing contrast agents or carriers with theranostic properties.
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