Journal
CELL REPORTS MEDICINE
Volume 1, Issue 6, Pages -Publisher
CELL PRESS
DOI: 10.1016/j.xcrm.2020.100098
Keywords
-
Categories
Funding
- National Institutes of Health [1R35GM134867]
- Montana State University (MSU) Agricultural Experimental Station
- M.J. Murdock Charitable Trust
- Gianforte Family Foundation
- MSU Office of the Vice President for Research
Ask authors/readers for more resources
SARS-CoV-2 has recently been detected in feces, which indicates that wastewater may be used to monitor viral prevalence in the community. Here, we use RT-qPCR to monitor wastewater for SARS-CoV-2 RNA over a 74-day time course. We show that changes in SARS-CoV-2 RNA concentrations follow symptom onset gathered by retrospective interview of patients but precedes clinical test results. In addition, we determine a nearly complete (98.5%) SARS-CoV-2 genome sequence from wastewater and use phylogenetic analysis to infer viral ancestry. Collectively, this work demonstrates how wastewater can be used as a proxy to monitor viral prevalence in the community and how genome sequencing can be used for genotyping viral strains circulating in a community.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available