Research Progress of C-reactive Protein Analysis

C-reactive protein (CRP) is an important biomarker for acute inflammation and infection, and is widely used clinically for the assessment of various diseases and the monitoring of patients. conditions. At present, the clinical test methods for CRP mainly include immunoturbidimetry, enzyme-linked immunosorbent assays, and lateral flow assays. In recent years, the developments in analysis theory and improvements in materials science have resulted in the continual emergence of analytical methods and techniques, such as biosensor technology and microfluidics. Here, we summarized the development and application of CRP analytical methods and focused on the developments during the last five years. In addition, we predicted the research directions for novel CRP assays and provided new ideas for the development of CRP analytical methods with high sensitivity and specificity that could meet clinical needs.