4.7 Article

A near-infrared fluorescent probe for imaging of nitroxyl in living cells

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2020.118680

Keywords

BODIPY; Nitroxyl; Fluorescent sensing and imaging; Near-infrared; Dyes and pigments

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Funding

  1. National Natural Science Foundation of China [21971115]
  2. Key University Science Research Project of Jiangsu Province [17KJA150004]

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A BODIPY-based NIR fluorescent probe, NitroxylBDP, for the rapid and specific, detection of HNO has been designed and synthesized. The merits of NIR fluorescence, and stable fluorescence output against pH changes, and good membrane permeability, enable the probe to serve as an ideal indicator for tracking HNO in living systems. (C) 2020 Elsevier B.V. All rights reserved.

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