Journal
INDUSTRIAL CROPS AND PRODUCTS
Volume 95, Issue -, Pages 6-17Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.indcrop.2016.10.007
Keywords
Phenolics; Carotenoid profiles; Antioxidant activities; Calpain activity; Anti-proliferative effect
Categories
Funding
- Algerian Ministry of High Education and Scientific Research
- Institut National de la Sante et de la Recherche Medicale (INSERM)
- SIRIC from Institut National du Cancer
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Ficus carica L, Ceratonia siliqua L and Quercus ilex L are natural products that are used as an advantageous rich source of bioactive compounds of high economic value because of its use in cosmetic, pharmaceutical and agriculture industries. These crops were studied for its phytochemical contents and were investigated for antioxidant activities and its effects on. reactive oxygen species (ROS) production, calpain activity and antiproliferative effects. Results showed that extremely high total contents of phenolics, flavonoids and ortho-diphenols were detected in Quercus ilex, while proanthocyanidin level was higher in Ficus carica. Ceratonia siliqua pods showed more carotenoids and had the highest lightness value (L*). Quercus ilex and Ceratonia siliqua extracts were very effective in scavenging free radicals. The best hydroxyl radical scavenging activity was attributed to Quercus ilex with 80.51 +/- 0.20% while nitric oxide assay showed no significant differences between extracts. Ficus carica presented a higher reducing ability with 638.23 +/- 0.43 mg gallic acid equivalents/100 g, while Quercus ilex was very potent in reducing power assays. Percentages of metal chelating capacities of Quercus ilex and Rap carica extracts were 87.87 +/- 0.34 and 73.17 +/- 0.16%, respectively. These two samples were also able to scavenge hydrogen peroxide efficiently. At 250 mu g/mL, Quercus ilex presented the bestxanthine oxidase inhibition, 89.81 +/- 0.36%. Ceratonia siliqua and Quercus ilex extracts presented the best capacities of ROS inhibition and reduced cell viability in a concentration dependent manner. All samples decreased calpain activity. These extracts could be further exploited as a source of natural products with antioxidant and anticancer effects. (C) 2016 Elsevier B.V. All rights reserved.
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