Journal
RSC ADVANCES
Volume 10, Issue 52, Pages 31243-31250Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0ra05115b
Keywords
-
Categories
Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [NRF-2013R1A1A2012823, NRF-2020R1I1A1A0106444511]
Ask authors/readers for more resources
We have developed a low-cost, portable lab-on-a-valve (LOV) integrated microdevice for the detection of pathogens in primary-diagnosis settings. This system was designed for field-based pathogen detection based on the aggregation of gold nanoparticles induced by a switchable linker. A three-way valve, which has attracted much attention as a functional mesofluidic platform for pressure-driven flow, has been designed as a universal reaction platform that combines the functions of fluid flow and a reaction chamber. In addition, we obtain rapid and enhanced visual signals by the use of a syringe filter to remove gold nano-aggregates (Au NAs). Using this device,SalmonellaTyphimurium down to 10(1)CFU mL(-1)can be visually detected within 30 min by performing a simple operation that requires no complex equipment. This prototype device has great potential for use in the semi-quantitative and qualitative identification of pathogens in on-site primary diagnoses.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available