A review of hemodynamic parameters in cerebral aneurysm

A cerebral aneurysm is a localized dilation that weakens the wall of a blood vessel in the brain. This condition comes in the form of abnormal widening, ballooning or in the form of a bleb. Gaining an understanding of the initiation, growth, and rupture of cerebral aneurysm has played a critical role in finding treatments that prevent the possibility of mortality and morbidity. Cerebral aneurysm develops as a result of the thinning of artery wall, and it is often difficult to diagnose prior to its rupture that leads to several fatal diseases, including brain damage, hemorrhagic stroke, behavioral inconsistency, and eye movement disturbance. A computational fluid dynamic study of cerebral aneurysm employs blood flow simulation wherein hemodynamic parameters indicate the rupture status of a vessel. These hemodynamic parameters actually trigger the biological factors of blood flow in the brain vessels with aneurysm. This paper offers a review of these hemodynamic parameters, and it elucidates the correlation of these parameters with cerebral aneurysm. Specifically, this review highlights the hemodynamic parameters that are related to the formation, growth, and morphological features, namely, size and shape, of cerebral aneurysm.