4.7 Article

Simultaneous regulation of optical properties and cellular behaviors of gold nanoclusters by pre-engineering the biotemplates

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 77, Pages 11414-11417

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc04039h

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Funding

  1. National Natural Science Foundation of China [21705129]
  2. Fundamental Research Fund for the Central University [3102019jcc005, 3102019GHJD001]
  3. Research Fund of the State Key Laboratory of Solidification Processing (NPU) [2020-QZ-01]

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Herein, we reported a new strategy to simultaneously regulate both the physicochemical properties and biological behaviors of fabricated nanomaterials. Upon precisely pre-tailoring the number of charged groups of bovine serum albumin (BSA), the resultant BSA-templated gold nanoclusters (BSA-AuNCs) exhibit remarkably different fluorescence properties and strong biotemplate-dependent cellular uptake behavior.

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