4.7 Review

Roles of Biomarkers in Myocardial Fibrosis

Journal

AGING AND DISEASE
Volume 11, Issue 5, Pages 1157-1173

Publisher

INT SOC AGING & DISEASE
DOI: 10.14336/AD.2020.0604

Keywords

biomarkers; collagen; myocardial fibrosis; review

Funding

  1. National Natural Science Foundation of China [81904118, 81603559]
  2. Young Elite Scientists Sponsorship Program by CAST [CACM-2018-QNRC2-B04]

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Myocardial fibrosis is observed in various cardiovascular diseases and plays a key role in the impairment of cardiac function. Endomyocardial biopsy, as the gold standard for the diagnosis of myocardial fibrosis, has limitations in terms of clinical application. Therefore, biomarkers have been recommended for noninvasive assessment of myocardial fibrosis. This review discusses the role of biomarkers in myocardial fibrosis from the perspective of collagen.

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