4.3 Article

A BOOTSTRAP LASSO plus PARTIAL RIDGE METHOD TO CONSTRUCT CONFIDENCE INTERVALS FOR PARAMETERS IN HIGH-DIMENSIONAL SPARSE LINEAR MODELS

Journal

STATISTICA SINICA
Volume 30, Issue 3, Pages 1333-1355

Publisher

STATISTICA SINICA
DOI: 10.5705/ss.202018.0131

Keywords

Bootstrap; confidence interval; high-dimensional inference; Lasso plus partial ridge; model selection consistency

Funding

  1. NSF [DMS-1613002, DMS-1228246, DMS-1613338, DBI-1846216]
  2. AFOSR [FA955014-1-0016]
  3. National Natural Science Foundation of China [11701316]
  4. Hellman Fellowship
  5. PhRMA Foundation Research Starter Grant in Informatics
  6. Sloan Research Fellowship
  7. Johnson & Johnson WiSTEM2D Award
  8. NIH/NIGMS [R01GM120507]

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Constructing confidence intervals for the coefficients of high-dimensional sparse linear models remains a challenge, mainly because of the complicated limiting distributions of the widely used estimators, such as the lasso. Several methods have been developed for constructing such intervals. Bootstrap lasso+ols is notable for its technical simplicity, good interpretability, and performance that is comparable with that of other more complicated methods. However, bootstrap lasso+ols depends on the beta-min assumption, a theoretic criterion that is often violated in practice. Thus, we introduce a new method, called bootstrap lasso+partial ridge, to relax this assumption. Lasso+partial ridge is a two-stage estimator. First, the lasso is used to select features. Then, the partial ridge is used to refit the coefficients. Simulation results show that bootstrap lasso+partial ridge outperforms bootstrap lasso+ols when there exist small, but nonzero coefficients, a common situation that violates the beta-min assumption. For such coefficients, the confidence intervals constructed using bootstrap lasso+partial ridge have, on average, 50% larger coverage probabilities than those of bootstrap lasso+ols. Bootstrap lasso+partial ridge also has, on average, 35% shorter confidence interval lengths than those of the desparsified lasso methods, regardless of whether the linear models are misspecified. Additionally, we provide theoretical guarantees for bootstrap lasso+partial ridge under appropriate conditions, and implement it in the R package HDCI.

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